Journal: Engineering Microbiology

Article Title: Cross-kingdom noncoding RNA regulation facilitates Nosema bombycis proliferation

doi: 10.1016/j.engmic.2026.100278

Figure Lengend Snippet: NbLNC2914 acts as a miRNA sponge that inhibits the expression of bmo-miR-2808a-3p.

Article Snippet: Next, the total RNAs were used for cDNA synthesis with the PrimeScriptTM RT reagent Kit (Takara, Japan) and miRNA first-strand cDNA synthesis (Tailing Reaction) (Sangon Biotech, China).

Techniques: Expressing

Journal: Oncology Letters

Article Title: Gastrointestinal cancer with indeterminate 18 F-FDG PET/CT findings: Diagnostic efficacy analysis of 68 Ga-FAPI-04 PET/MRI

doi: 10.3892/ol.2026.15647

Figure Lengend Snippet: Comparison of 18 F-FDG and 68 Ga-FAPI-04 MIP images. MIP images of 5 patients clearly demonstrating marked differences between the two tracers, including visualization of (A) metastasis in the pancreaticoduodenum, (B) anastomotic recurrence, (C) cerebellar metastasis, (D) splenic metastasis and (E) peritoneal metastasis. Two orange arrows (upper and lower) constitute a pair, indicating the visual comparison of the same lesion in the same patient on MIP images obtained with two different tracers. MIP, maximum intensity projection; FAPI, fibroblast-activation protein inhibitor; 68 Ga, gallium 68; FDG, fluorodeoxyglucose; 18 F, fluorine 18.

Article Snippet: The 18 F-FDG synthesis was performed by Yantai Dongcheng Pharmaceutical Group Co., Ltd. All products underwent comprehensive quality control, including radiochemical purity, specific activity and sterility tests, and met the required standards before clinical use.

Techniques: Comparison, Activation Assay

Journal: Oncology Letters

Article Title: Gastrointestinal cancer with indeterminate 18 F-FDG PET/CT findings: Diagnostic efficacy analysis of 68 Ga-FAPI-04 PET/MRI

doi: 10.3892/ol.2026.15647

Figure Lengend Snippet: 68 Ga-FAPI-04 PET/MRI vs. 18 F-FDG PET/CT: Quantitative comparison of primary tumors and anastomotic sites. Primary tumor focus of (A) a patient with gastrointestinal cancer, (B) the anastomotic recurrence of 1 patient, (C) the metastatic abdominal wall incision of 1 patient and (D and E) the benign anastomoses of 2 patients. The white arrows appear in paired upper and lower positions, indicating the uptake comparison of the two tracers at the same anatomical site. The orange arrows also appear in paired upper and lower positions, corresponding to the MRI T1WI and T2WI signals of the same lesion, respectively. The color bar shows a consistent color scale (7.0) for all images. Histograms are respectively used to display the statistical differences in the TBR_blood_pool of the primary tumor foci of (F) the two tracers, (G) the recurrent anastomoses and the metastatic abdominal wall incisions, as well as (H) the benign anastomoses. The numbers on the histograms represent the sample size of each group. **P<0.01. TBR_blood_pool, tumor-to-blood-pool ratio; ns, not significant; FAPI, fibroblast-activation protein inhibitor; 68 Ga, gallium 68; FDG, fluorodeoxyglucose; 18 F, fluorine 18; PET, positron emission tomography; MRI, magnetic resonance imaging; CT, computed tomography.

Article Snippet: The 18 F-FDG synthesis was performed by Yantai Dongcheng Pharmaceutical Group Co., Ltd. All products underwent comprehensive quality control, including radiochemical purity, specific activity and sterility tests, and met the required standards before clinical use.

Techniques: Positron Emission Tomography-Computed Tomography, Comparison, Activation Assay, Positron Emission Tomography, Magnetic Resonance Imaging, Computed Tomography

Journal: Oncology Letters

Article Title: Gastrointestinal cancer with indeterminate 18 F-FDG PET/CT findings: Diagnostic efficacy analysis of 68 Ga-FAPI-04 PET/MRI

doi: 10.3892/ol.2026.15647

Figure Lengend Snippet: 68 Ga-FAPI-04 PET/MRI vs. 18 F-FDG PET/CT: Quantitative comparison of metastatic lymph nodes. Comparison between 68 Ga-FAPI-04 PET/MRI and 18 F-FDG PET/CT for metastatic lymph nodes located in the (A) cervical, (B) thoracic, (C) abdominal and (D) pelvic regions, respectively. The white arrows appear in paired upper and lower positions, indicating the uptake comparison of the two tracers at the same anatomical site. The orange arrows also appear in paired upper and lower positions, corresponding to the MRI T1WI and T2WI signals of the same lesion, respectively. The color bar shows a consistent color scale (7.0) for all images. Histograms show the statistical differences in TBR_blood_pool between the two tracers for metastatic lymph nodes: (E) Treatment-naive lymph nodes, (F) postsurgical and other treated lymph nodes, (G) all metastatic lymph nodes, as well as for (H) cervical, (I) thoracic, (J) abdominal and (K) pelvic regions, respectively. The numbers on the histograms represent the sample size of each group. ***P<0.001. TBR_blood_pool, tumor-to-blood-pool ratio; FAPI, fibroblast-activation protein inhibitor; 68 Ga, gallium 68; FDG, fluorodeoxyglucose; 18 F, fluorine 18; PET, positron emission tomography; MRI, magnetic resonance imaging; CT, computed tomography.

Article Snippet: The 18 F-FDG synthesis was performed by Yantai Dongcheng Pharmaceutical Group Co., Ltd. All products underwent comprehensive quality control, including radiochemical purity, specific activity and sterility tests, and met the required standards before clinical use.

Techniques: Positron Emission Tomography-Computed Tomography, Comparison, Activation Assay, Positron Emission Tomography, Magnetic Resonance Imaging, Computed Tomography

Journal: Oncology Letters

Article Title: Gastrointestinal cancer with indeterminate 18 F-FDG PET/CT findings: Diagnostic efficacy analysis of 68 Ga-FAPI-04 PET/MRI

doi: 10.3892/ol.2026.15647

Figure Lengend Snippet: 68 Ga-FAPI-04 PET/MRI vs. 18 F-FDG PET/CT: quantitative comparison of benign lymph nodes. Comparison between 68 Ga-FAPI-04 PET/MRI and 18 F-FDG PET/CT for benign lymph nodes located in the (A) cervical, (B) thoracic, (C) abdominal and (D) pelvic regions, respectively. The white arrows appear in paired upper and lower positions, indicating the uptake comparison of the two tracers at the same anatomical site. The orange arrows also appear in paired upper and lower positions, corresponding to the MRI T1WI and T2WI signals of the same lesion, respectively. The color bar shows a consistent color scale (7.0) for all images. Histograms show the statistical differences in TBR_blood_pool between the two tracers for benign lymph nodes: (E) Treatment-naive lymph nodes, (F) postsurgical and other treated lymph nodes, (G) all benign lymph nodes, as well as for (H) cervical, (I) thoracic, (J) abdominal and (K) pelvic regions, respectively. The numbers on the histograms represent the sample size of each group. ***P<0.001. ns, not significant; TBR_blood_pool, tumor-to-blood-pool ratio; FAPI, fibroblast-activation protein inhibitor; 68 Ga, gallium 68; FDG, fluorodeoxyglucose; 18 F, fluorine 18; PET, positron emission tomography; MRI, magnetic resonance imaging; CT, computed tomography.

Article Snippet: The 18 F-FDG synthesis was performed by Yantai Dongcheng Pharmaceutical Group Co., Ltd. All products underwent comprehensive quality control, including radiochemical purity, specific activity and sterility tests, and met the required standards before clinical use.

Techniques: Positron Emission Tomography-Computed Tomography, Comparison, Activation Assay, Positron Emission Tomography, Magnetic Resonance Imaging, Computed Tomography

Journal: Oncology Letters

Article Title: Gastrointestinal cancer with indeterminate 18 F-FDG PET/CT findings: Diagnostic efficacy analysis of 68 Ga-FAPI-04 PET/MRI

doi: 10.3892/ol.2026.15647

Figure Lengend Snippet: 68 Ga-FAPI-04 PET/MRI vs. 18 F-FDG PET/CT: Quantitative comparison of distant metastasis. Comparison between 68 Ga-FAPI-04 PET/MRI and 18 F-FDG PET/CT for the metastases of gastrointestinal tumors in the (A) peritoneum, (B) spleen, (C) pancreatic head and peritoneum metastasis, (D) liver, (E) bone, (F) cerebellum and (G) kidney. The color bar shows a consistent color scale (7.0) for all images. (H) The histogram shows the comparison of the TBR_blood_pool of the two tracers for distant organ metastases. The numbers on the histograms represent the sample size of each group. ***P<0.001. TBR_blood_pool, tumor-to-blood-pool ratio; FAPI, fibroblast-activation protein inhibitor; 68 Ga, gallium 68; FDG, fluorodeoxyglucose; 18 F, fluorine 18; PET, positron emission tomography; MRI, magnetic resonance imaging; CT, computed tomography.

Article Snippet: The 18 F-FDG synthesis was performed by Yantai Dongcheng Pharmaceutical Group Co., Ltd. All products underwent comprehensive quality control, including radiochemical purity, specific activity and sterility tests, and met the required standards before clinical use.

Techniques: Positron Emission Tomography-Computed Tomography, Comparison, Activation Assay, Positron Emission Tomography, Magnetic Resonance Imaging, Computed Tomography